Myokardia (MYOK) versus CymaBay Therapeutics (CBAY) Head to Head Contrast

Myokardia (NASDAQ: CBAY) and CymaBay Therapeutics (NASDAQ:CBAY) are both medical companies, but which is the superior business? We will contrast the two businesses based on the strength of their institutional ownership, profitability, earnings, risk, dividends, valuation and analyst recommendations.

Valuation and Earnings

This table compares Myokardia and CymaBay Therapeutics’ gross revenue, earnings per share (EPS) and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
Myokardia $22.50 million 100.66 -$45.95 million ($1.40) -40.32
CymaBay Therapeutics $10.00 million 73.46 -$27.55 million ($0.79) -15.75



CymaBay Therapeutics has lower revenue, but higher earnings than Myokardia. Myokardia is trading at a lower price-to-earnings ratio than CymaBay Therapeutics, indicating that it is currently the more affordable of the two stocks.

Analyst Ratings

This is a breakdown of current recommendations and price targets for Myokardia and CymaBay Therapeutics, as provided by MarketBeat.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Myokardia 0 0 7 0 3.00
CymaBay Therapeutics 0 0 9 0 3.00

Myokardia currently has a consensus price target of $73.57, indicating a potential upside of 30.33%. CymaBay Therapeutics has a consensus price target of $21.88, indicating a potential upside of 75.84%. Given CymaBay Therapeutics’ higher possible upside, analysts clearly believe CymaBay Therapeutics is more favorable than Myokardia.

Profitability

This table compares Myokardia and CymaBay Therapeutics’ net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Myokardia -249.22% -21.16% -18.19%
CymaBay Therapeutics N/A -37.39% -32.54%

Institutional and Insider Ownership

84.3% of Myokardia shares are held by institutional investors. Comparatively, 82.3% of CymaBay Therapeutics shares are held by institutional investors. 4.7% of Myokardia shares are held by company insiders. Comparatively, 4.5% of CymaBay Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company will outperform the market over the long term.

Volatility and Risk

Myokardia has a beta of 3.5, suggesting that its stock price is 250% more volatile than the S&P 500. Comparatively, CymaBay Therapeutics has a beta of 1.9, suggesting that its stock price is 90% more volatile than the S&P 500.

Summary

Myokardia beats CymaBay Therapeutics on 7 of the 13 factors compared between the two stocks.

Myokardia Company Profile

MyoKardia, Inc., a clinical stage biopharmaceutical company, discovers, develops, and commercializes therapies for the treatment of rare cardiovascular diseases. Its lead product candidate is mavacamten, an orally administered small molecule, which has completed Phase II clinical trial that is designed to reduce left ventricular contractility to potentially alleviate the functional consequences and symptoms of hypertrophic cardiomyopathy (HCM) and prevent or reverse HCM progression. The company also develops MYK-491, an orally-administered small molecule, which is in Phase I b clinical trial that is designed to restore normal contractility in the diseased dilated cardiomyopathy (DCM) heart. Its three preclinical programs include HCM-2 that is used to reduce cardiac muscle contractility to normal levels in HCM patients; DCM-2, which is used to enhance cardiac muscle contractility to normal levels in genetic DCM patients; and LUS-1 that is used to counteract a muscle disruption that results in impaired relaxation of the heart, a biomechanical defect found in specific HCM and genetic DCM patient subgroups, as well as in other less common heritable cardiomyopathies. The company has a strategic collaboration with Aventis Inc. for the research, development, and commercialization of pharmaceutical products to treat, prevent, and diagnose HCM and DCM, as well as additional indications. MyoKardia, Inc. was founded in 2012 and is headquartered in South San Francisco, California.

CymaBay Therapeutics Company Profile

CymaBay Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing and providing therapies to treat liver and other chronic diseases. Its lead product candidate is seladelpar, a selective agonist of peroxisome proliferator-activated receptor delta, which has completed Phase II clinical study for the treatment of primary biliary cholangitis, as well as patients with nonalcoholic steatohepatitis. The company also develops arhalofenate, which has completed five Phase II clinical trials for the treatment of patients with gout; and MBX-2982, an oral G-protein coupled receptor agonist that has completed one Phase II clinical trial for therapeutic indications. It has licensing agreement with Kowa Pharmaceuticals America, Inc. for the development and commercialization of arhalofenate in the United States; and Janssen Pharmaceuticals, Inc. to develop and discover undisclosed metabolic disease target agonists for the treatment of type II diabetes and other disorders, as well as a license and development agreement with DiaTex, Inc. to develop and commercialize therapeutic products comrprising halofenate and its enantiomers, derivatives, and analogs for the treatment of diseases. The company was formerly known as Metabolex, Inc. CymaBay Therapeutics, Inc. was incorporated in 1988 and is headquartered in Newark, California.

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